Night-Shift Manufacturing Leader

Amgen

Amgen seeks a Night-Shift Manufacturing Leader to oversee 12-hour operations in a drug substance facility, ensuring GMP compliance and team performance.

Last checked on September 13, 2026. We may earn a commission when you click through.

✓ Attractive salary range ✓ Leadership role with growth opportunities ✓ Focus on continuous improvement

Night-Shift Manufacturing Leader

Amgen

Updated 19 hours ago

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Holly Springs $106k–$144k/yr Part-Time

This role is suitable for experienced manufacturing leaders seeking a well-compensated position in the biotech sector. However, the demanding night shift may not appeal to everyone, particularly those valuing daytime hours.

About this role

Amgen seeks a Night-Shift Manufacturing Leader to oversee 12-hour operations in a drug substance facility, ensuring GMP compliance and team performance.

About the Company

Amgen is a leading biotechnology company focused on discovering, developing, and delivering innovative medicines.

Key Highlights

✓ Competitive salary range of $106K–$144K annually
✓ Full oversight of manufacturing personnel and operations
✓ Focus on GMP compliance and continuous improvement
✓ Collaborative environment with cross-functional teams
✓ Managerial role with leadership responsibilities

💡 Honest Take: While the position offers a solid salary, be prepared for the intensity of a 12-hour night shift and the high expectations in a fast-paced manufacturing environment. Some employees report a challenging work-life balance, especially with the long hours.

Pros

✓ Attractive salary range
✓ Leadership role with growth opportunities
✓ Focus on continuous improvement
✓ Engaging work environment
✓ Support from cross-functional teams

Cons

✗ Long 12-hour shifts
✗ Night shift may disrupt personal life
✗ High-pressure work environment
✗ Requires significant leadership experience
✗ Potential for burnout due to workload

Best For: Professionals in the biotech or manufacturing sectors who thrive under pressure and have strong leadership skills.

Watch Out: The demanding night shift schedule may not suit everyone and could impact work-life balance significantly.

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Expert Review

This position at Amgen offers an attractive salary, ranging from $106K to $144K annually, which is competitive in the biotech industry. The role requires overseeing a 12-hour night shift, demanding strong leadership and compliance with GMP standards. It's a fast-paced environment that emphasizes continuous improvement, making it thrive under pressure.

However, potential candidates should be aware of the challenges posed by night shifts. Many employees report difficulties in maintaining a healthy work-life balance due to extended hours. The company culture encourages collaboration, but the pressure to meet production goals can be intense, leading to potential burnout.

For anyone considering this role, it's essential to assess personal preferences for night work and readiness for the demands of a leadership position in a high-stakes environment. According to Amgen's site, the focus on employee development is a plus, but the realities of the job may differ from expectations. Overall, this position is individuals who are committed to the biotech field and can handle the demanding nature of night operations.